Epigenome Editing - Methods and Protocols (Vol. 2)

Prof. Marianne G. Rots and Prof. Albert Jeltsch edited a book on Epigenome Editing. It appears in the highly successful “Methods in Molecular Biology” series published by Humana Press, which is well recognized since almost 30 years for comprehensive and reliable protocols. In this book, the concepts and applications of epigenome editing are presented by leading scientists in the field. Beginning with some general and topical reviews, the collection continues by covering the design of DNA-binding devices, optimization of the effector domains, readout of epigenome marks, and approaches for delivery at the cellular and organismal level. Chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Methods and Protocols will be of great assistance to people new to the field but also to those already engaged, as epigenetic editing is still a relatively unexplored field with many issues to be resolved.

Information about the book:
Epigenome Editing - Methods and Protocols
Series: Methods in Moleclar Biology (Volume 1767)
DOI: 10.1007/978-1-4939-7774-1
Hardcover ISBN: 978-1-4939-7773-4
Publisher: Springer International Publishing
588 pages